Basic Information
ID: ALA4380948
Type: Binding
Description: Inhibition of MNK1/MNK2 in human HeLa cells overexpressing eIF4E assessed as reduction in eIF4E phosphorylation at Ser209 residue after 2 hrs by Alphascreen SureFly assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4380948
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.42 | 3.34 | 3.34 |
| 325.41 | 3.23 | 3.23 |
| 350.42 | 3.64 | 3.64 |
| 392.46 | 3.46 | 3.46 |
| 256.30 | 2.63 | 2.63 |
| 336.40 | 3.04 | 3.04 |
| 362.43 | 3.90 | 3.90 |
| 341.41 | 2.47 | 2.47 |
| 336.40 | 3.33 | 3.33 |
| 313.36 | 1.99 | 1.99 |
| 324.34 | 1.81 | 1.81 |
| 378.43 | 3.07 | 3.07 |
| 364.45 | 4.08 | 4.08 |