Basic Information
ID: ALA4380985
Type: Functional
Description: Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins followed by C3a addition and measured at 1 sec interval for => 200 secs by Fluo-3 AM dye-based FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4380985
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 412.49 | 1.67 | 1.67 |
| 374.47 | 1.79 | 1.79 |
| 451.55 | 2.77 | 2.77 |
| 538.67 | 3.79 | 3.79 |
| 533.48 | 4.99 | 4.99 |
| 500.62 | 4.53 | 4.53 |
| 416.55 | 2.93 | 2.93 |
| 533.48 | 4.99 | 4.99 |
| 519.45 | 4.68 | 4.68 |
| 496.59 | 3.09 | 3.09 |
| 464.59 | 3.68 | 3.68 |
| 486.54 | 3.65 | 3.65 |
| 464.59 | 3.68 | 3.68 |
| 510.62 | 3.39 | 3.39 |
| 500.57 | 3.96 | 3.96 |
| 450.65 | 4.58 | 4.58 |
| 388.49 | 2.35 | 2.35 |
| 402.52 | 2.74 | 2.74 |
| 526.66 | 5.04 | 5.04 |
| 504.66 | 4.25 | 4.25 |
| 526.66 | 5.04 | 5.04 |
| 519.45 | 4.68 | 4.68 |
| 451.55 | 2.77 | 2.77 |
| 456.61 | 3.91 | 3.91 |
| 478.62 | 3.76 | 3.76 |
| 414.53 | 3.04 | 3.04 |
| 450.56 | 3.37 | 3.37 |
| 529.46 | 4.14 | 4.14 |