Assay Report Card

Basic Information

ID: ALA4381025

Type: Binding

Description: Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells interaction with Cy5-p22phox149-162 incubated for 10 mins by fluorescence polarization competition assay

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA4381025

Total(74)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
129.16	2.23	2.23
213.28	1.64	1.64
212.30	2.25	2.25
94.12	0.66	0.66
143.19	2.42	2.42
274.18
144.18	1.82	1.82
144.18	1.82	1.82
144.18	1.82	1.82
144.18	1.82	1.82
95.11	0.06	0.06
150.21	1.88	1.88
144.18	1.82	1.82
144.18	1.82	1.82
144.18	1.82	1.82
158.20	2.28	2.28
160.18	1.52	1.52
163.22	0.49	0.49
232.28	2.23	2.23
145.16	1.53	1.53
186.21	2.19	2.19
174.20	1.83	1.83
143.19	2.54	2.54
247.73	2.30	2.30
158.20	2.13	2.13
227.31	1.95	1.95
160.18	1.52	1.52
254.72	4.14	4.14
216.28	2.60	2.60
227.31	1.95	1.95
281.28	2.66	2.66
213.28	1.64	1.64
233.36	1.28	1.28
243.31	1.65	1.65
614.80	2.94	2.94
327.43	3.60	3.60
242.33	1.57	1.57
228.29	2.38	2.38
229.33	2.52	2.52
204.32	2.00	2.00
232.28	2.23	2.23
227.31	2.81	2.81
178.62	2.47	2.47
230.31	1.79	1.79
279.34	3.44	3.44
229.28	1.65	1.65
233.36	1.55	1.55
202.26	2.29	2.29
281.28	2.66	2.66
317.44	3.87	3.87
256.35	3.78	3.78
228.30	1.23	1.23
217.27	1.88	1.88
226.32	3.53	3.53
128.22	0.29	0.29
284.75	4.05	4.05
284.75	4.05	4.05
219.33	1.29	1.29
478.55	3.46	3.46
250.30	3.40	3.40
273.34	1.66	1.66
172.23	2.30	2.30
241.34	2.30	2.30
478.55	3.46	3.46
270.34	1.49	1.49
241.34	2.34	2.34
232.28	2.23	2.23
206.29	0.98	0.98
284.75	4.05	4.05
232.28	1.66	1.66
232.28	2.23	2.23
158.20	1.69	1.69
292.18	2.41	2.41
269.35	2.21	2.21