Basic Information
ID: ALA4381547
Type: Functional
Description: In vivo inhibition of acid sphingomyelinase in Sprague-Dawley rat model of reserpine-induced depression assessed as residual enzyme activity in hippocampus at 24 mg/kg, ip administered twice daily for 2 weeks measured post-last dose by NBD-sphingomyelin substrate-based fluorescence assay (Rvb = 73%)
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4381547
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 344.75 | 3.69 | 3.69 |