ID: ALA4381830
Type: Binding
Description: Inhibition of 5HT2A receptor-mediated psycho-plastogenic activity in Sprague-Dawley rat cortical neurons assessed as decrease in dendritic arbor complexity at 1 uM pretreated with ketanserin for 1 hr followed by compound addition and ketanserin addition after 1 hr supplemented with fresh neurobasal medium measured after 71 hrs by Alexa Fluor 488 dye based imaging analysis
Format: BAO_0000357
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Target: Serotonin 2a (5-HT2a) receptor(ALA322)
Document: ALA4376893
Inhibition of 5HT2A receptor-mediated psycho-plastogenic activity in Sprague-Dawley rat cortical neurons assessed as decrease in dendritic arbor complexity at 1 uM pretreated with ketanserin for 1 hr followed by compound addition and ketanserin addition after 1 hr supplemented with fresh neurobasal medium measured after 71 hrs by Alexa Fluor 488 dye based imaging analysis: 1
Bioactivity
Activity Types for Assay ALA4381830
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
218.30 | 2.28 | 2.28 |