Inhibition of recombinant human IDO1 using L-tryptophan as substrate incubated under dark conditions measured after 60 mins by fluorescence microplate...

Basic Information

ID: ALA4381946

Type: Binding

Description: Inhibition of recombinant human IDO1 using L-tryptophan as substrate incubated under dark conditions measured after 60 mins by fluorescence microplate reader assay

Format: BAO_0000357

Organism: Homo sapiens

Target: Indoleamine 2,3-dioxygenase(ALA4685)

Document: ALA4376897

Inhibition of recombinant human IDO1 using L-tryptophan as substrate incubated under dark conditions measured after 60 mins by fluorescence microplate reader assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4381946

IC50

Total(57)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
158.16	1.62	1.62
271.64	1.69	1.69
475.34	4.55	4.55
441.49	3.79	3.79
425.49	4.09	4.09
445.91	4.44	4.44
439.52	4.40	4.40
686.63	6.78	6.78
443.48	4.23	4.23
479.46	4.80	4.80
432.43	4.07	4.07
414.44	3.93	3.93
637.76	6.02	6.02
429.45	3.92	3.92
445.91	4.44	4.44
430.89	4.44	4.44
490.36	4.55	4.55
425.49	4.09	4.09
445.91	4.44	4.44
430.89	4.44	4.44
675.73	7.03	7.03
429.45	3.92	3.92
479.46	4.80	4.80
489.37	4.86	4.86
504.38	4.86	4.86
426.47	3.80	3.80
493.33	4.69	4.69
459.93	4.75	4.75
475.34	4.55	4.55
414.44	3.93	3.93
490.36	4.55	4.55
410.47	4.10	4.10
464.44	4.81	4.81
411.46	3.78	3.78
410.47	4.10	4.10
396.45	3.79	3.79
430.89	4.44	4.44
424.50	4.41	4.41
475.34	4.55	4.55
426.47	3.80	3.80
410.47	4.10	4.10
441.49	3.79	3.79
426.47	3.80	3.80
464.44	4.81	4.81
456.50	3.81	3.81
444.92	4.75	4.75
493.33	4.69	4.69
471.51	3.80	3.80
428.46	4.24	4.24
414.44	3.93	3.93
441.49	3.79	3.79
425.49	4.09	4.09
429.45	3.92	3.92
508.35	4.69	4.69
490.36	4.55	4.55
508.35	4.69	4.69
447.44	4.06	4.06