Antischistosomal activity against Schistosoma mansoni infected in NMRI mouse assessed as reduction in total adult worm burden at 400 mg/kg, po adminis...

Basic Information

ID: ALA4382063

Type: Functional

Description: Antischistosomal activity against Schistosoma mansoni infected in NMRI mouse assessed as reduction in total adult worm burden at 400 mg/kg, po administered as single dose starting on day 49 post-infection and measured at 28 days post treatment relative to control

Format: BAO_0000218

Organism: Schistosoma mansoni

Target:  Schistosoma mansoni(ALA612893)

Document:  ALA4376900

Antischistosomal activity against Schistosoma mansoni infected in NMRI mouse assessed as reduction in total adult worm burden at 400 mg/kg, po administered as single dose starting on day 49 post-infection and measured at 28 days post treatment relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
284.352.192.19
428.483.813.81
456.585.815.81
525.623.573.57
442.555.115.11
448.945.295.29
400.474.584.58
523.654.354.35
620.743.053.05
471.553.753.75
497.635.105.10
533.645.355.35
442.555.415.41
491.613.633.63
442.555.415.41
458.514.334.33
430.503.613.61
384.474.874.87
471.553.753.75
483.395.945.94
511.593.343.34
549.694.694.69
450.484.884.88