Protac activity at CRBN/ABL in human K562 cells assessed as reduction in ABL protein levels at 100 nM incubated for 36 hrs by Western blot analysis

Basic Information

ID: ALA4382070

Type: Binding

Description: Protac activity at CRBN/ABL in human K562 cells assessed as reduction in ABL protein levels at 100 nM incubated for 36 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: K562

Target: Protein cereblon/Tyrosine-protein kinase ABL1(ALA4523750)

Document: ALA4376901

Protac activity at CRBN/ABL in human K562 cells assessed as reduction in ABL protein levels at 100 nM incubated for 36 hrs by Western blot analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4382070

Activity

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
953.49	7.83	7.83
981.54	8.61	8.61

Parent Molecular Weight

ALogP

Polar Surface Area

953.49

7.83

981.54

8.61

Protac activity at CRBN/ABL in human K562 cells assessed as reduction in ABL protein levels at 100 nM incubated for 36 hrs by Western blot analysis

Basic Information

Activity Charts

Compound Summary