Assay Report Card

Basic Information

ID: ALA4382085

Type: Binding

Description: Protac activity at CRBN/BCR-ABL in human K562 cells assessed as reduction in BCR-ABL protein levels pre-treated with lenalidomide followed by compound addition at 250 nM incubated for 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: K562

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
981.548.618.61