Basic Information
ID: ALA4382086
Type: Binding
Description: Protac activity at CRBN/ABL in human K562 cells assessed as reduction in ABL protein levels pre-treated with lenalidomide followed by compound addition at 250 nM incubated for 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562
Target: Protein cereblon/Tyrosine-protein kinase ABL1(ALA4523750)
Document: ALA4376901
Protac activity at CRBN/ABL in human K562 cells assessed as reduction in ABL protein levels pre-treated with lenalidomide followed by compound addition at 250 nM incubated for 24 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4382086
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 981.54 | 8.61 | 8.61 |