Basic Information
ID: ALA4382087
Type: Binding
Description: Protac activity at CRBN/BCR-ABL in human K562 cells assessed as reduction in BCR-ABL protein levels pre-treated with NEDD8-activating enzyme (NAE) inhibitor MLN4924 followed by compound addition at 250 nM incubated for 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA4382087
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 981.54 | 8.61 | 8.61 |