Basic Information
ID: ALA4382307
Type: Binding
Description: Inhibition of EGFR T790M/L858R double mutant (unknown origin) transfected in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTS assay
Organism: Homo sapiens
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA4382307
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 494.98 | 4.55 | 4.55 |
| 558.15 | 6.36 | 6.36 |
| 499.62 | 4.51 | 4.51 |
| 585.71 | 4.42 | 4.42 |
| 603.15 | 4.00 | 4.00 |
| 537.61 | 4.34 | 4.34 |
| 694.60 | 3.95 | 3.95 |
| 602.16 | 4.93 | 4.93 |
| 567.72 | 4.28 | 4.28 |
| 572.05 | 5.00 | 5.00 |
| 693.61 | 4.88 | 4.88 |
| 604.18 | 5.15 | 5.15 |
| 568.70 | 3.35 | 3.35 |
| 555.60 | 4.48 | 4.48 |
| 586.69 | 3.48 | 3.48 |
| 663.50 | 4.95 | 4.95 |