Basic Information
ID: ALA4382912
Type: Binding
Description: Inhibition of human N-terminal His6-tagged GGPPS Y246D mutant expressed in Escherichia coli BL21(DE3) using [14C]-IPP and FPP as substrates after 10 mins by scintillation counting
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4382912
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.11 | -0.37 | -0.37 |
| 448.48 | 6.20 | 6.20 |
| 325.18 | 0.74 | 0.74 |
| 401.28 | 2.41 | 2.41 |
| 401.28 | 2.41 | 2.41 |
| 469.27 | 3.43 | 3.43 |
| 520.40 | 3.66 | 3.66 |
| 520.40 | 3.66 | 3.66 |
| 520.40 | 3.66 | 3.66 |
| 534.43 | 3.97 | 3.97 |
| 538.39 | 3.80 | 3.80 |
| 550.43 | 3.67 | 3.67 |
| 550.43 | 3.67 | 3.67 |
| 568.42 | 3.81 | 3.81 |