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Therapeutic index, ratio EC50 for human MRC5 SV2 cells to EC50 for Trypanosoma cruzi Tulahuen CL2 intracellular amastigotes

Basic Information

ID: ALA4383193

Type: Toxicity

Description: Therapeutic index, ratio EC50 for human MRC5 SV2 cells to EC50 for Trypanosoma cruzi Tulahuen CL2 intracellular amastigotes

Format: BAO_0000219

Target:  ADMET(ALA612558)

Document:  ALA4382200

Therapeutic index, ratio EC50 for human MRC5 SV2 cells to EC50 for Trypanosoma cruzi Tulahuen CL2 intracellular amastigotes: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
260.251.111.11
251.25-0.95-0.95
360.801.971.97
378.792.112.11
354.411.941.94
368.442.442.44
395.252.632.63
332.401.701.70
390.831.981.98
374.832.282.28
371.351.231.23
395.252.632.63
326.361.321.32
360.801.971.97
394.352.342.34
330.391.611.61
394.352.342.34
340.381.631.63
340.381.631.63
376.800.950.95
395.252.632.63
356.381.331.33
344.351.461.46
354.411.881.88
378.792.112.11
376.422.472.47
410.352.222.22
390.831.981.98
374.832.282.28
362.341.601.60