ID: ALA4383193
Type: Toxicity
Description: Therapeutic index, ratio EC50 for human MRC5 SV2 cells to EC50 for Trypanosoma cruzi Tulahuen CL2 intracellular amastigotes
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA4382200
Therapeutic index, ratio EC50 for human MRC5 SV2 cells to EC50 for Trypanosoma cruzi Tulahuen CL2 intracellular amastigotes: 1
Bioactivity
Activity Types for Assay ALA4383193
Ratio EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
260.25 | 1.11 | 1.11 |
251.25 | -0.95 | -0.95 |
360.80 | 1.97 | 1.97 |
378.79 | 2.11 | 2.11 |
354.41 | 1.94 | 1.94 |
368.44 | 2.44 | 2.44 |
395.25 | 2.63 | 2.63 |
332.40 | 1.70 | 1.70 |
390.83 | 1.98 | 1.98 |
374.83 | 2.28 | 2.28 |
371.35 | 1.23 | 1.23 |
395.25 | 2.63 | 2.63 |
326.36 | 1.32 | 1.32 |
360.80 | 1.97 | 1.97 |
394.35 | 2.34 | 2.34 |
330.39 | 1.61 | 1.61 |
394.35 | 2.34 | 2.34 |
340.38 | 1.63 | 1.63 |
340.38 | 1.63 | 1.63 |
376.80 | 0.95 | 0.95 |
395.25 | 2.63 | 2.63 |
356.38 | 1.33 | 1.33 |
344.35 | 1.46 | 1.46 |
354.41 | 1.88 | 1.88 |
378.79 | 2.11 | 2.11 |
376.42 | 2.47 | 2.47 |
410.35 | 2.22 | 2.22 |
390.83 | 1.98 | 1.98 |
374.83 | 2.28 | 2.28 |
362.34 | 1.60 | 1.60 |