Basic Information
ID: ALA4383380
Type: Binding
Description: Partial agonist activity at human alpha7 nAChR at 100 uM at -60 mV holding potential incubated for 1 sec followed by 60 secs compound washout relative to acetylcholine
Format: BAO_0000357
Organism: Homo sapiens
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA4382203
Partial agonist activity at human alpha7 nAChR at 100 uM at -60 mV holding potential incubated for 1 sec followed by 60 secs compound washout relative to acetylcholine: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4383380
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.49 | 4.74 | 4.74 |
| 351.28 | 4.38 | 4.38 |
| 350.38 | 4.09 | 4.09 |
| 412.96 | 4.24 | 4.24 |
| 316.83 | 3.73 | 3.73 |
| 316.83 | 3.73 | 3.73 |
| 296.41 | 3.38 | 3.38 |
| 351.28 | 4.38 | 4.38 |
| 350.38 | 4.09 | 4.09 |
| 296.41 | 3.38 | 3.38 |
| 412.96 | 4.24 | 4.24 |
| 351.28 | 4.38 | 4.38 |
| 296.41 | 3.38 | 3.38 |
| 351.28 | 4.38 | 4.38 |
| 316.83 | 3.73 | 3.73 |
| 350.38 | 4.09 | 4.09 |
| 351.28 | 4.38 | 4.38 |