Assay Report Card

Basic Information

ID: ALA4383508

Type: Functional

Description: Antitumor activity against mouse BAF3 cells expressing BCR/ABL T315I mutant allografted in nu/nu mouse assessed as tumor growth inhibition at 25 to 50 mg/kg, po administered via gavage for 14 days by TUNEL staining based assay

Organism: Mus musculus

Cell type: BaF3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
580.686.026.02