Basic Information
ID: ALA4383545
Type: Functional
Description: Antiinflammatory activity in mouse primary peritoneal macrophages assessed as inhibition of LPS-induced TNF-alpha production at 10 uM preincubated for 30 mins followed by LPS addition and measured after 24 hrs by ELISA relative to control
Format: BAO_0000219
Organism: Mus musculus
Cell type: Peritoneal macrophage
Target: Peritoneal macrophage(ALA5314330)
Document: ALA4382208
Antiinflammatory activity in mouse primary peritoneal macrophages assessed as inhibition of LPS-induced TNF-alpha production at 10 uM preincubated for 30 mins followed by LPS addition and measured after 24 hrs by ELISA relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4383545
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 411.26 | 4.22 | 4.22 |
| 357.48 | 4.32 | 4.32 |
| 285.37 | 3.32 | 3.32 |
| 327.45 | 4.31 | 4.31 |
| 299.40 | 3.63 | 3.63 |
| 341.48 | 4.62 | 4.62 |
| 427.26 | 3.92 | 3.92 |
| 397.24 | 3.91 | 3.91 |
| 301.37 | 3.02 | 3.02 |
| 271.34 | 3.01 | 3.01 |
| 375.49 | 5.47 | 5.47 |
| 339.34 | 4.03 | 4.03 |
| 315.39 | 3.33 | 3.33 |
| 353.36 | 4.34 | 4.34 |
| 303.36 | 3.46 | 3.46 |
| 299.40 | 3.63 | 3.63 |
| 330.37 | 3.23 | 3.23 |
| 369.36 | 4.04 | 4.04 |
| 305.79 | 3.66 | 3.66 |
| 321.40 | 4.16 | 4.16 |
| 319.81 | 3.97 | 3.97 |
| 299.39 | 3.63 | 3.63 |
| 277.37 | 3.07 | 3.07 |
| 321.40 | 4.46 | 4.46 |
| 289.33 | 3.15 | 3.15 |
| 327.45 | 4.58 | 4.58 |
| 347.44 | 4.68 | 4.68 |
| 364.26 | 4.08 | 4.08 |
| 209.27 | 1.58 | 1.58 |
| 305.79 | 3.96 | 3.96 |
| 285.37 | 3.32 | 3.32 |