Basic Information
ID: ALA4383637
Type: Binding
Description: Inhibition of Leishmania donovani Top1B expressed in Top1B deficient Saccharomyces cerevisiae EKY3 assessed as decrease in relaxation of supercoiled pSK DNA preincubated for 15 mins followed by DNA addition and measured after 2 to 16 mins by agarose gel electrophoresis
Format: BAO_0000019
Organism: Leishmania donovani
Target: Unchecked(ALA612545)
Document: ALA4382214
Inhibition of Leishmania donovani Top1B expressed in Top1B deficient Saccharomyces cerevisiae EKY3 assessed as decrease in relaxation of supercoiled pSK DNA preincubated for 15 mins followed by DNA addition and measured after 2 to 16 mins by agarose gel electrophoresis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4383637
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.59 | 7.58 | 7.58 |
| 533.58 | 7.60 | 7.60 |
| 513.62 | 7.45 | 7.45 |
| 515.59 | 7.02 | 7.02 |
| 546.63 | 7.04 | 7.04 |
| 499.53 | 7.35 | 7.35 |
| 539.54 | 7.43 | 7.43 |
| 517.58 | 7.46 | 7.46 |
| 487.56 | 7.27 | 7.27 |
| 531.60 | 8.36 | 8.36 |