Basic Information
ID: ALA4383712
Type: Binding
Description: Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring reduction in TNFalpha secretion pretreated for 30 mins followed by LPS stimulation for 24 hrs by electrochemiluminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4383712
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.47 | 3.13 | 3.13 |
| 459.58 | 4.81 | 4.81 |
| 354.45 | 1.64 | 1.64 |
| 382.50 | 2.42 | 2.42 |
| 326.39 | 0.86 | 0.86 |
| 506.64 | 5.23 | 5.23 |
| 326.39 | 0.86 | 0.86 |
| 382.50 | 2.42 | 2.42 |
| 354.45 | 1.64 | 1.64 |
| 506.64 | 5.23 | 5.23 |
| 459.58 | 4.81 | 4.81 |