Basic Information
ID: ALA4383745
Type: Functional
Description: Antiproliferative activity against human NCI-H1975 cells harboring EGFR T790M/L858R double mutant after 72 hrs by MTS assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: NCI-H1975(ALA614348)
Document: ALA4382217
Antiproliferative activity against human NCI-H1975 cells harboring EGFR T790M/L858R double mutant after 72 hrs by MTS assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4383745
GI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.62 | 4.51 | 4.51 |
| 534.57 | 4.25 | 4.25 |
| 542.62 | 4.56 | 4.56 |
| 485.55 | 3.91 | 3.91 |
| 487.56 | 4.16 | 4.16 |
| 498.59 | 3.66 | 3.66 |
| 526.65 | 4.44 | 4.44 |
| 521.53 | 4.51 | 4.51 |
| 540.60 | 4.31 | 4.31 |
| 486.58 | 3.56 | 3.56 |
| 549.58 | 5.28 | 5.28 |
| 523.54 | 4.75 | 4.75 |
| 500.61 | 3.90 | 3.90 |
| 536.59 | 4.50 | 4.50 |
| 562.63 | 5.03 | 5.03 |
| 513.60 | 4.69 | 4.69 |
| 486.58 | 3.88 | 3.88 |
| 506.64 | 3.97 | 3.97 |