Basic Information
ID: ALA4383747
Type: Unassigned
Description: Selectivity index, ratio of GI50 for human A431 cells harboring WT EGFR to GI50 for human NCI-H1975 cells harboring EGFR T790M/L858R double mutant
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4382217
Selectivity index, ratio of GI50 for human A431 cells harboring WT EGFR to GI50 for human NCI-H1975 cells harboring EGFR T790M/L858R double mutant: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4383747
RatioGI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.62 | 4.51 | 4.51 |
| 534.57 | 4.25 | 4.25 |
| 542.62 | 4.56 | 4.56 |
| 485.55 | 3.91 | 3.91 |
| 487.56 | 4.16 | 4.16 |
| 498.59 | 3.66 | 3.66 |
| 526.65 | 4.44 | 4.44 |
| 521.53 | 4.51 | 4.51 |
| 540.60 | 4.31 | 4.31 |
| 549.58 | 5.28 | 5.28 |
| 523.54 | 4.75 | 4.75 |
| 500.61 | 3.90 | 3.90 |
| 536.59 | 4.50 | 4.50 |
| 562.63 | 5.03 | 5.03 |
| 513.60 | 4.69 | 4.69 |
| 506.64 | 3.97 | 3.97 |