Basic Information
ID: ALA4383980
Type: Binding
Description: Inhibition of Mycobacterium tuberculosis H37Rv DNA gyrase A/B expressed in Escherichia coli assessed as reduction in supercoiling of relaxed pBR322 DNA substrate measured after 60 mins by ethidium bromide staining based agarose gel electrophoresis method
Organism: Mycobacterium tuberculosis H37Rv
Activity Charts
Bioactivity
Activity Types for Assay ALA4383980
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.74 | 3.17 | 3.17 |
| 350.29 | 2.43 | 2.43 |
| 381.39 | 4.25 | 4.25 |
| 368.28 | 2.57 | 2.57 |
| 319.32 | 2.83 | 2.83 |