Basic Information
ID: ALA4384180
Type: Binding
Description: Inhibition of human TOPK using MBP as substrate after 2 hrs in presence of [gamma-33P]-ATP by filter-binding method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4384180
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.44 | 4.44 | 4.44 |
| 392.52 | 5.09 | 5.09 |
| 374.44 | 4.13 | 4.13 |
| 392.89 | 5.33 | 5.33 |
| 406.87 | 4.40 | 4.40 |
| 384.48 | 4.66 | 4.66 |
| 364.83 | 4.73 | 4.73 |
| 386.50 | 5.29 | 5.29 |
| 386.50 | 5.03 | 5.03 |
| 358.44 | 4.42 | 4.42 |
| 372.47 | 4.98 | 4.98 |
| 372.47 | 4.73 | 4.73 |
| 358.44 | 4.69 | 4.69 |
| 386.50 | 5.29 | 5.29 |
| 398.51 | 4.96 | 4.96 |
| 370.45 | 4.35 | 4.35 |
| 400.52 | 5.34 | 5.34 |
| 372.47 | 4.73 | 4.73 |
| 358.44 | 4.69 | 4.69 |
| 441.58 | 5.02 | 5.02 |
| 400.52 | 5.34 | 5.34 |
| 362.40 | 4.52 | 4.52 |
| 360.41 | 4.09 | 4.09 |
| 401.51 | 4.49 | 4.49 |
| 414.51 | 4.66 | 4.66 |
| 344.41 | 4.38 | 4.38 |
| 434.92 | 5.01 | 5.01 |
| 406.91 | 5.37 | 5.37 |
| 376.43 | 4.56 | 4.56 |
| 380.83 | 4.43 | 4.43 |
| 358.44 | 4.69 | 4.69 |
| 372.47 | 4.73 | 4.73 |
| 400.93 | 4.49 | 4.49 |
| 386.45 | 4.06 | 4.06 |
| 402.49 | 4.73 | 4.73 |
| 358.44 | 4.69 | 4.69 |
| 422.91 | 5.08 | 5.08 |
| 388.47 | 4.69 | 4.69 |
| 378.86 | 4.77 | 4.77 |
| 386.50 | 5.29 | 5.29 |
| 394.86 | 4.48 | 4.48 |
| 400.52 | 5.34 | 5.34 |
| 408.89 | 5.04 | 5.04 |
| 372.47 | 4.73 | 4.73 |