Basic Information
ID: ALA4384383
Type: Unassigned
Description: Selectivity index, ratio of IC50 for wild-type human N-terminal GST-tagged EGFR (695 to end residues) expressed in baculovirus infected Sf9 insect cells to IC50 for human N-terminal GST-tagged EGFR T790M/L858R double mutant (695 to end residues) expressed in baculovirus infected Sf9 insect cells
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4382243
Selectivity index, ratio of IC50 for wild-type human N-terminal GST-tagged EGFR (695 to end residues) expressed in baculovirus infected Sf9 insect cells to IC50 for human N-terminal GST-tagged EGFR T790M/L858R double mutant (695 to end residues) expressed in baculovirus infected Sf9 insect cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4384383
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.91 | 4.28 | 4.28 |
| 499.62 | 4.51 | 4.51 |
| 557.58 | 4.62 | 4.62 |
| 575.63 | 3.32 | 3.32 |
| 583.57 | 4.33 | 4.33 |
| 549.63 | 3.62 | 3.62 |
| 517.59 | 3.37 | 3.37 |
| 515.57 | 3.31 | 3.31 |
| 487.56 | 3.36 | 3.36 |
| 432.48 | 3.67 | 3.67 |
| 555.56 | 4.38 | 4.38 |
| 545.60 | 3.32 | 3.32 |
| 519.61 | 3.61 | 3.61 |
| 492.54 | 3.69 | 3.69 |
| 537.62 | 4.51 | 4.51 |
| 489.58 | 3.60 | 3.60 |
| 547.62 | 3.37 | 3.37 |