Basic Information
ID: ALA4384519
Type: Binding
Description: Inhibition of human AC8 expressed in HEK293 cells assessed as decrease in A23187-stimulated cAMP accumulation at 30 uM preincubated for 30 mins followed by A23187 stimulation and measured after 1 hr by fluorescence assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4384519
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 313.29 | 3.14 | 3.14 |
| 317.71 | 3.78 | 3.78 |
| 349.39 | 3.88 | 3.88 |
| 333.27 | 4.01 | 4.01 |
| 430.46 | 3.30 | 3.30 |
| 271.30 | 3.05 | 3.05 |
| 313.29 | 3.14 | 3.14 |
| 299.37 | 3.93 | 3.93 |
| 301.25 | 3.27 | 3.27 |
| 311.32 | 3.69 | 3.69 |
| 313.31 | 3.37 | 3.37 |
| 285.35 | 3.68 | 3.68 |
| 301.33 | 3.06 | 3.06 |
| 297.29 | 3.44 | 3.44 |
| 369.40 | 3.48 | 3.48 |
| 323.35 | 3.78 | 3.78 |
| 301.35 | 3.38 | 3.38 |
| 353.33 | 2.77 | 2.77 |
| 317.41 | 4.09 | 4.09 |
| 329.38 | 3.84 | 3.84 |
| 311.32 | 3.74 | 3.74 |
| 323.31 | 2.76 | 2.76 |
| 317.40 | 3.77 | 3.77 |
| 271.32 | 3.37 | 3.37 |
| 350.20 | 3.81 | 3.81 |
| 305.76 | 4.02 | 4.02 |
| 289.31 | 3.51 | 3.51 |
| 381.39 | 3.55 | 3.55 |
| 301.25 | 3.27 | 3.27 |
| 329.40 | 4.16 | 4.16 |
| 289.31 | 3.51 | 3.51 |
| 283.26 | 3.13 | 3.13 |
| 301.25 | 3.27 | 3.27 |
| 255.23 | 2.58 | 2.58 |
| 337.34 | 3.07 | 3.07 |
| 362.16 | 3.89 | 3.89 |