Basic Information
ID: ALA4384523
Type: ADME
Description: Cytotoxicity against HEK293 cells expressing human AC1 at 30 uM preincubated for 30 mins followed by A23187 stimulation and measured after 1 hr by CellTiter-Glo luminescent cell viability assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4384523
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 337.35 | 4.01 | 4.01 |
| 313.29 | 3.14 | 3.14 |
| 319.36 | 3.87 | 3.87 |
| 351.26 | 4.15 | 4.15 |
| 349.39 | 3.88 | 3.88 |
| 317.71 | 3.78 | 3.78 |
| 349.39 | 3.88 | 3.88 |
| 333.27 | 4.01 | 4.01 |
| 430.46 | 3.30 | 3.30 |
| 271.30 | 3.05 | 3.05 |
| 313.29 | 3.14 | 3.14 |
| 333.39 | 4.18 | 4.18 |
| 398.26 | 4.63 | 4.63 |
| 417.39 | 4.90 | 4.90 |
| 299.37 | 3.93 | 3.93 |
| 301.25 | 3.27 | 3.27 |
| 311.32 | 3.69 | 3.69 |
| 313.31 | 3.37 | 3.37 |
| 285.35 | 3.68 | 3.68 |
| 301.33 | 3.06 | 3.06 |
| 297.29 | 3.44 | 3.44 |
| 402.20 | 3.52 | 3.52 |
| 369.34 | 4.40 | 4.40 |
| 428.47 | 5.27 | 5.27 |
| 391.31 | 3.78 | 3.78 |
| 369.40 | 3.48 | 3.48 |
| 323.35 | 3.78 | 3.78 |
| 301.35 | 3.38 | 3.38 |
| 347.42 | 5.04 | 5.04 |
| 365.29 | 4.46 | 4.46 |
| 353.33 | 2.77 | 2.77 |
| 317.41 | 4.09 | 4.09 |
| 339.32 | 4.39 | 4.39 |
| 337.35 | 4.01 | 4.01 |
| 365.46 | 4.59 | 4.59 |
| 329.38 | 3.84 | 3.84 |
| 311.32 | 3.74 | 3.74 |
| 365.29 | 4.46 | 4.46 |
| 323.31 | 2.76 | 2.76 |
| 387.36 | 4.89 | 4.89 |
| 347.42 | 4.43 | 4.43 |
| 317.40 | 3.77 | 3.77 |
| 271.32 | 3.37 | 3.37 |
| 350.20 | 3.81 | 3.81 |
| 305.76 | 4.02 | 4.02 |
| 289.31 | 3.51 | 3.51 |
| 351.36 | 3.38 | 3.38 |
| 299.37 | 3.99 | 3.99 |
| 381.39 | 3.55 | 3.55 |
| 301.25 | 3.27 | 3.27 |
| 353.34 | 4.70 | 4.70 |
| 353.81 | 4.52 | 4.52 |
| 329.40 | 4.16 | 4.16 |
| 395.44 | 4.86 | 4.86 |
| 353.34 | 4.70 | 4.70 |
| 289.31 | 3.51 | 3.51 |
| 377.44 | 4.65 | 4.65 |
| 283.26 | 3.13 | 3.13 |
| 359.36 | 4.80 | 4.80 |
| 301.25 | 3.27 | 3.27 |
| 255.23 | 2.58 | 2.58 |
| 350.22 | 4.13 | 4.13 |
| 381.29 | 4.16 | 4.16 |
| 337.34 | 3.07 | 3.07 |
| 359.36 | 4.80 | 4.80 |
| 362.16 | 3.89 | 3.89 |
| 401.39 | 5.19 | 5.19 |
| 401.39 | 5.19 | 5.19 |