Basic Information
ID: ALA4384734
Type: Binding
Description: Antagonist activity at human TRPV4 expressed in HEK cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10 mins followed by agonist addition by Fluo-4-AM dye-based FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Transient receptor potential cation channel subfamily V member 4(ALA3119)
Document: ALA4382258
Antagonist activity at human TRPV4 expressed in HEK cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10 mins followed by agonist addition by Fluo-4-AM dye-based FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4384734
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.37 | 1.44 | 1.44 |
| 413.28 | 2.68 | 2.68 |
| 461.35 | 2.07 | 2.07 |
| 491.37 | 1.44 | 1.44 |
| 491.37 | 1.44 | 1.44 |
| 491.37 | 1.44 | 1.44 |