Basic Information
ID: ALA4384751
Type: Functional
Description: Reversal of heart failure-induced pulmonary edema in Sprague-Dawley rat assessed as inhibition of GSK1016790A-induced increase in lung wet weight to body weight ratio at 0.02 to 0.21 ug/kg, iv bolus loading dose followed by 0.3 to 2.3 ug/kg/min, iv continuous infusion dose for 60 mins prior to agonist administration
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4384751
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.37 | 1.44 | 1.44 |