Basic Information
ID: ALA4384762
Type: Functional
Description: Reversal of heart failure-induced pulmonary edema in Sprague-Dawley rat assessed as inhibition of GSK1016790A-induced increase in lung wet weight to body weight ratio at 0.09 to 0.78 mg/kg, iv bolus loading dose followed by 0.07 to 0.6 ug/kg/min, iv continuous infusion dose for 60 mins prior to agonist administration
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4384762
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.38 | 0.80 | 0.80 |