Basic Information
ID: ALA4384769
Type: Binding
Description: Antagonist activity at human TRPV4 expressed in BHK/AC9 cells assessed as inhibition of GSK634775-induced calcium immobilization pre-incubated for 10 mins followed by agonist addition by Fluo-4-AM dye-based FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4384769
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 492.36 | 0.83 | 0.83 |
| 491.37 | 1.44 | 1.44 |
| 509.36 | 1.57 | 1.57 |
| 525.91 | 1.20 | 1.20 |
| 457.92 | 0.18 | 0.18 |
| 490.39 | 1.40 | 1.40 |
| 491.38 | 0.80 | 0.80 |
| 490.39 | 2.07 | 2.07 |
| 490.39 | 2.07 | 2.07 |
| 481.94 | 0.65 | 0.65 |
| 491.38 | 0.80 | 0.80 |
| 481.94 | 0.65 | 0.65 |