Assay Report Card

Basic Information

ID: ALA4384939

Type: Binding

Description: Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
487.58-1.43-1.43
271.362.812.81
390.480.250.25
406.44-0.93-0.93
289.291.911.91
355.535.155.15
395.475.395.39
372.474.284.28
519.65-1.52-1.52
489.620.400.40
300.411.961.96
283.382.952.95
244.292.002.00
182.221.581.58
376.46-0.14-0.14
312.293.023.02
447.58-1.75-1.75
537.64-0.69-0.69
505.57-0.79-0.79
305.383.213.21
294.353.153.15