Basic Information
ID: ALA4384944
Type: Binding
Description: Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in LPS-induced creatine kinase levels at 10 to 20 uM preincubated for 1 hr followed by LPS stimulation for 5 hrs by NADH detection based colorimetric analysis
Format: BAO_0000219
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Target: Toll-like receptor 4(ALA4523480)
Document: ALA4382262
Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in LPS-induced creatine kinase levels at 10 to 20 uM preincubated for 1 hr followed by LPS stimulation for 5 hrs by NADH detection based colorimetric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4384944
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.62 | 0.40 | 0.40 |
| 505.57 | -0.79 | -0.79 |