Assay Report Card

Basic Information

ID: ALA4385183

Type: Functional

Description: Protection against cisplatin-induced acute liver injury in Sprague-Dawley rat assessed as reduction in cleaved caspase-3 level in kidneys at 1 mg/kg pretreated for 24 hrs followed by cisplatin challenge and subsequent qd dosing for 5 days measured 7 days post cisplatin challenge by Western blot analysis

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
494.597.577.57