Basic Information
ID: ALA4385197
Type: Binding
Description: Inhibition of calf thymus topoisomerase-1 assessed as reduction in cleavage complex formation by measuring nicked form DNA level using supercoiled pBR322 DNA as substrate after 30 mins by agarose gel electrophoresis assay (Rvb = 47%)
Organism: Bos taurus
Activity Charts
Bioactivity
Activity Types for Assay ALA4385197
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 472.62 | 5.41 | 5.41 |
| 486.61 | 4.90 | 4.90 |