ID: ALA4385238
Type: ADME
Description: Prodrug activation in human HepG2 cell lysates assessed as NQO1-mediated CX-21 formation at 10 uM after 60 mins in presence of NADPH and NQO1 inhibitor dicoumarol by HPLC analysis
Organism: Homo sapiens
Cell type: HepG2
Subcellular Fraction: Lysate
Bioactivity
Activity Types for Assay ALA4385238
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
592.69 | 3.88 | 3.88 |