Basic Information
ID: ALA4385239
Type: ADME
Description: Prodrug activation in human HepG2 cell lysates assessed as NQO1-mediated triptolide formation at 10 uM after 60 mins in presence of NADPH and NQO1 inhibitor dicoumarol by HPLC analysis
Organism: Homo sapiens
Cell type: HepG2
Subcellular Fraction: Lysate
Activity Charts
Bioactivity
Activity Types for Assay ALA4385239
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 592.69 | 3.88 | 3.88 |