Basic Information
ID: ALA4385295
Type: Binding
Description: Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrate addition and measured every 20 secs for 10 mins in presence of C57BL/6 mouse plasma by fluorescence assay
Organism: Homo sapiens
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4385295
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.47 | 2.23 | 2.23 |
| 703.22 | 3.47 | 3.47 |
| 624.55 | 4.65 | 4.65 |
| 507.62 | 2.55 | 2.55 |
| 555.66 | 3.34 | 3.34 |
| 479.57 | 1.77 | 1.77 |
| 523.62 | 1.79 | 1.79 |
| 628.71 | 3.52 | 3.52 |
| 610.67 | 2.09 | 2.09 |
| 497.56 | 2.62 | 2.62 |
| 500.58 | 3.37 | 3.37 |
| 613.70 | 2.85 | 2.85 |
| 590.11 | 4.00 | 4.00 |
| 661.19 | 3.70 | 3.70 |
| 561.59 | 3.10 | 3.10 |