Assay Report Card

Basic Information

ID: ALA4385302

Type: ADME

Description: Induction of read through activity at cricket paralysis virus-internal ribosome entry site codon UGG assessed as increase in octapeptide formation from FKVRQ-tRNAGln at EC50 to 2 times EC50 measured after 20 mins in presence of Typ-tRNA, Leu-tRNA and [35S]-Met-tRNA by co-sedimentation assay

Organism: Cricket paralysis virus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
543.530.000.00
248.28-2.54-2.54
315.312.992.99
284.253.243.24
496.56-5.61-5.61
630.70-6.14-6.14
482.53-6.00-6.00
569.61-7.40-7.40
482.53-5.88-5.88
1015.23
887.05-6.91-6.91
502.53-5.75-5.75
1143.40
482.53-6.00-6.00
1271.58
435.484.214.21
758.88-6.53-6.53