Basic Information
ID: ALA4385320
Type: Binding
Description: Inhibition of full-length human GST-tagged ASK1 expressed in baculovirus expression system using biotinylated STK Substrate 3 preincubated for 10 mins followed by ATP addition and measured after 5 hrs by TR-FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Mitogen-activated protein kinase kinase kinase 5(ALA5285)
Document: ALA4382281
Inhibition of full-length human GST-tagged ASK1 expressed in baculovirus expression system using biotinylated STK Substrate 3 preincubated for 10 mins followed by ATP addition and measured after 5 hrs by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4385320
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.39 | 3.01 | 3.01 |
| 349.39 | 3.16 | 3.16 |
| 349.39 | 3.07 | 3.07 |
| 412.25 | 3.30 | 3.30 |
| 429.48 | 3.57 | 3.57 |
| 420.47 | 2.60 | 2.60 |