Basic Information
ID: ALA4385466
Type: Binding
Description: Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Arachidonate 5-lipoxygenase(ALA215)
Document: ALA4382289
Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4385466
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.37 | 7.13 | 7.13 |
| 442.37 | 7.03 | 7.03 |
| 423.93 | 6.48 | 6.48 |
| 409.90 | 6.17 | 6.17 |
| 444.34 | 6.83 | 6.83 |
| 423.93 | 6.48 | 6.48 |
| 458.37 | 7.13 | 7.13 |
| 389.48 | 5.83 | 5.83 |
| 458.37 | 7.13 | 7.13 |
| 423.93 | 6.48 | 6.48 |
| 409.90 | 6.17 | 6.17 |
| 423.93 | 6.48 | 6.48 |
| 423.93 | 6.48 | 6.48 |
| 409.90 | 6.17 | 6.17 |
| 389.48 | 5.83 | 5.83 |
| 458.37 | 7.13 | 7.13 |
| 460.41 | 7.54 | 7.54 |
| 440.36 | 7.42 | 7.42 |
| 423.93 | 6.48 | 6.48 |
| 444.34 | 6.83 | 6.83 |
| 375.45 | 5.52 | 5.52 |