Basic Information
ID: ALA4385685
Type: Binding
Description: Inhibition of voltage-dependent L-type calcium channel in human U373MG cells assessed as protection against oxygen glucose deprivation/reperfusion-induced injury by measuring recovery of cell viability at 20 uM administered at onset of reperfusion period measured after 16 hrs by alamar blue assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Voltage-gated L-type calcium channel(ALA2095229)
Document: ALA4385592
Inhibition of voltage-dependent L-type calcium channel in human U373MG cells assessed as protection against oxygen glucose deprivation/reperfusion-induced injury by measuring recovery of cell viability at 20 uM administered at onset of reperfusion period measured after 16 hrs by alamar blue assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4385685
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.34 | 2.18 | 2.18 |
| 437.52 | 3.95 | 3.95 |
| 429.42 | 3.30 | 3.30 |
| 562.99 | 4.22 | 4.22 |
| 517.99 | 4.31 | 4.31 |
| 528.54 | 3.57 | 3.57 |
| 453.52 | 3.65 | 3.65 |
| 483.55 | 3.66 | 3.66 |
| 453.52 | 3.65 | 3.65 |
| 415.39 | 3.00 | 3.00 |
| 491.49 | 4.66 | 4.66 |
| 507.49 | 4.54 | 4.54 |
| 511.60 | 4.44 | 4.44 |
| 514.54 | 4.47 | 4.47 |
| 469.54 | 4.56 | 4.56 |
| 483.57 | 4.87 | 4.87 |
| 562.44 | 4.42 | 4.42 |
| 580.62 | 4.68 | 4.68 |
| 545.02 | 5.29 | 5.29 |
| 505.52 | 4.84 | 4.84 |
| 520.44 | 5.73 | 5.73 |
| 614.44 | 6.08 | 6.08 |
| 590.50 | 5.20 | 5.20 |
| 530.99 | 4.99 | 4.99 |
| 503.98 | 5.22 | 5.22 |
| 590.50 | 5.20 | 5.20 |
| 590.50 | 5.20 | 5.20 |
| 487.53 | 4.70 | 4.70 |
| 548.43 | 5.33 | 5.33 |
| 487.53 | 4.70 | 4.70 |
| 485.99 | 5.08 | 5.08 |
| 599.88 | 6.29 | 6.29 |
| 575.44 | 5.09 | 5.09 |
| 469.54 | 4.56 | 4.56 |
| 525.63 | 4.75 | 4.75 |
| 593.49 | 6.20 | 6.20 |