Basic Information
ID: ALA4385775
Type: Binding
Description: Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 1 mM preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay relative to control
Organism: Human gammaherpesvirus 8
Activity Charts
Bioactivity
Activity Types for Assay ALA4385775
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 189.17 | 1.78 | 1.78 |
| 209.25 | 2.61 | 2.61 |
| 188.19 | 1.57 | 1.57 |
| 159.19 | 1.45 | 1.45 |
| 189.17 | 0.97 | 0.97 |
| 188.19 | 1.57 | 1.57 |
| 160.18 | 1.58 | 1.58 |
| 174.20 | 1.88 | 1.88 |
| 265.27 | 2.63 | 2.63 |
| 201.23 | 1.83 | 1.83 |
| 159.19 | 1.45 | 1.45 |
| 189.17 | 0.97 | 0.97 |
| 189.17 | 1.78 | 1.78 |
| 159.19 | 1.45 | 1.45 |
| 265.27 | 2.63 | 2.63 |
| 188.19 | 1.57 | 1.57 |
| 189.17 | 0.97 | 0.97 |
| 238.09 | 2.22 | 2.22 |
| 189.17 | 1.78 | 1.78 |
| 173.22 | 1.76 | 1.76 |