Basic Information
ID: ALA4385777
Type: Binding
Description: Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay
Organism: Human gammaherpesvirus 8
Activity Charts
Bioactivity
Activity Types for Assay ALA4385777
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 273.29 | 1.73 | 1.73 |
| 280.29 | 2.21 | 2.21 |
| 280.29 | 2.21 | 2.21 |
| 280.29 | 2.21 | 2.21 |
| 266.26 | 2.03 | 2.03 |
| 280.29 | 2.21 | 2.21 |