Assay Report Card

Basic Information

ID: ALA4385781

Type: Binding

Description: Inhibition of 5'-Dy682-labelled LBS1/LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 500 uM preincubated for 1 hr followed by 5'-Dy682-labelled LBS1 DNA addition and measured after 30 mins by electrophoretic mobility shift assay

Organism: Human gammaherpesvirus 8

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
273.291.731.73
280.292.212.21
280.292.212.21
280.292.212.21
266.262.032.03
280.292.212.21