Basic Information
ID: ALA4385807
Type: Binding
Description: Inhibition of recombinant human PDE9A2 catalytic domain (181 to 506 residues) expressed in Escherichia coli BL21 using 3H-cGMP as substrate after 15 mins by liquid scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4385807
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.45 | 1.28 | 1.28 |
| 360.42 | 0.94 | 0.94 |
| 380.40 | 1.90 | 1.90 |
| 362.41 | 1.61 | 1.61 |
| 318.38 | 1.12 | 1.12 |
| 358.45 | 2.05 | 2.05 |
| 387.49 | 1.20 | 1.20 |
| 362.46 | 1.57 | 1.57 |
| 387.49 | 1.20 | 1.20 |
| 332.41 | 1.51 | 1.51 |
| 344.42 | 1.66 | 1.66 |
| 360.42 | 0.89 | 0.89 |
| 358.45 | 2.09 | 2.09 |
| 362.41 | 1.61 | 1.61 |