Basic Information
ID: ALA4385839
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes using [14C]-dextromethorphan as substrate preincubated for 2 mins in presence of NADPH followed by substrate addition and measured after 10 mins by liquid scintillation counting method
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4385839
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.41 | 1.61 | 1.61 |