Basic Information
ID: ALA4385894
Type: Functional
Description: Agonist activity at human kappa-type opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding at 10 uM incubated for 1 hr by liquid scintillation counting method relative to U69593
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Kappa opioid receptor(ALA237)
Document: ALA4385600
Agonist activity at human kappa-type opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding at 10 uM incubated for 1 hr by liquid scintillation counting method relative to U69593: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4385894
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 285.34 | 1.20 | 1.20 |
| 586.53 | 4.68 | 4.68 |
| 536.98 | 4.44 | 4.44 |
| 545.60 | 4.22 | 4.22 |
| 530.59 | 4.74 | 4.74 |
| 572.62 | 4.57 | 4.57 |
| 546.59 | 4.36 | 4.36 |
| 560.61 | 4.57 | 4.57 |
| 546.59 | 4.18 | 4.18 |
| 608.66 | 5.37 | 5.37 |
| 502.53 | 3.79 | 3.79 |
| 532.56 | 3.79 | 3.79 |
| 559.59 | 3.74 | 3.74 |
| 518.53 | 3.49 | 3.49 |
| 516.56 | 4.35 | 4.35 |
| 516.56 | 4.09 | 4.09 |
| 573.61 | 4.13 | 4.13 |