Assay Report Card

Basic Information

ID: ALA4385958

Type: Functional

Description: Antitumor activity against Mcl1-sensitive human MV4-11 cells xenografted in NSGS mouse assessed as reduction of tumor burden in spleen at 50 to 100 mg/kg, ip administered daily for 3 weeks measured post-last dose by DAPI staining-based flow cytometry

Organism: Homo sapiens

Cell type: MV4-11

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
712.689.019.01