Basic Information
ID: ALA4386334
Type: Binding
Description: Inhibition of Rho/MRTF/SRF pathway (unknown origin) expressed in human PC3 cells assessed as reduction in Galpha12 Q231L-stimulated MRTF-selective SRE.L promoter-driven luciferase activity after overnight incubation by luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4386334
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.64 | 3.62 | 3.62 |
| 312.39 | 3.65 | 3.65 |
| 319.17 | 3.61 | 3.61 |
| 264.31 | 2.61 | 2.61 |
| 292.36 | 2.98 | 2.98 |
| 264.31 | 2.61 | 2.61 |
| 293.35 | 2.06 | 2.06 |
| 347.22 | 4.39 | 4.39 |
| 251.27 | 1.70 | 1.70 |
| 280.31 | 2.31 | 2.31 |
| 347.22 | 4.09 | 4.09 |
| 276.32 | 2.00 | 2.00 |
| 284.72 | 2.96 | 2.96 |
| 312.78 | 3.66 | 3.66 |
| 250.28 | 2.30 | 2.30 |
| 338.82 | 4.22 | 4.22 |
| 333.20 | 4.00 | 4.00 |
| 314.75 | 2.97 | 2.97 |
| 280.31 | 2.31 | 2.31 |
| 251.27 | 1.70 | 1.70 |
| 284.72 | 2.96 | 2.96 |
| 298.75 | 3.27 | 3.27 |
| 254.27 | 2.20 | 2.20 |
| 280.31 | 2.31 | 2.31 |
| 264.31 | 2.61 | 2.61 |
| 332.21 | 3.27 | 3.27 |
| 284.72 | 2.96 | 2.96 |
| 305.14 | 3.22 | 3.22 |