Basic Information
ID: ALA4386374
Type: Binding
Description: Inhibition of Rho/MRTF/SRF pathway in human primary dermal fibroblasts assessed as reduction in LPA-stimulated CTGF mRNA expression by measuring CTGF mRNA level at 10'-6 M preincubated for 72 hrs followed by LPA stimulation and measured after 1 hr by qPCR analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4386374
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.64 | 3.62 | 3.62 |
| 185.23 | 2.15 | 2.15 |